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. 2016 Dec 6;312(3):H515–H527. doi: 10.1152/ajpheart.00499.2016

Fig. 6.

Fig. 6.

Posttranslational regulation of Drp1 via LG exposure. A: phosphorylation of Drp1 at Ser 637 acts as an inhibitor of Drp1 activity. Expression of P-S637-Drp1 was analyzed in HUVECs treated with LG via Western blot. Overall, the data appear to support that LG exposure decreases phosphorylation at Ser 637 and may allow for increased Drp1 activity and subsequent fission. B: conversely, phosphorylation of Drp1 at Ser 616 acts as an activating event and LG exposure appears to increase phosphorylation at this site (*P < 0.01, N = 10).