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. 2016 Dec 6;312(3):H384–H391. doi: 10.1152/ajpheart.00528.2016

Fig. 6.

Fig. 6.

Effect of the Ca2+-calmodulin-dependent protein kinase II inhibitor, AIP. A: mean ICaL density-voltage relations for Sham myocytes with AIP included in the pipette solution (n/N = 4/1). Black-filled circles, AIP-dialyzed cells in control Tyrode’s; open circles, AIP-dialyzed cells in the presence of 100 nmol/l calyculin A. B: mean ICaL density-voltage relations for CAL myocytes with AIP included in the pipette solution (n/N = 5/1). Black-filled squares, AIP-dialyzed cells in control Tyrode’s; open squares, AIP-dialyzed cells in the presence of 100 nmol/l calyculin A. Data from Sham (A) and CAL (B) myocytes under control conditions (respectively, n/N = 33/12 and 31/10) are shown as, respectively, gray-filled circles and gray-filled squares, for comparison. ***P < 0.001, 2-way repeated-measures ANOVA and Bonferroni posttest vs. corresponding AIP control.