Table 3.
Univariable Regression for Sulfate Clearance |
Multivariable Regression for Sulfate Clearance |
|||
---|---|---|---|---|
Coefficient | P value | Coefficient | P value | |
Characteristics | ||||
Age | −0.545 | <0.001‡ | ||
Male | −11.354 | 0.066 | ||
Current smoker | −0.975 | 0.710 | ||
BMI | 0.141 | 0.703 | ||
Systolic blood pressure | 0.035 | 0.713 | ||
Diastolic blood pressure | 0.275 | 0.079 | ||
Heart rate | 0.188 | 0.281 | ||
Heart failure history | ||||
Duration HF* | −0.793 | 0.649 | ||
Ischemic etiology | −2.542 | 0.475 | ||
NYHA class II/III | −14.112 | 0.005‡ | ||
LVEF | −0.040 | 0.838 | ||
Treatment | ||||
β-Blocker | 10.838 | 0.243 | ||
MRA | −5.285 | 0.136 | ||
Diuretic | −9.389 | 0.003‡ | −4.322 | 0.048‡ |
Laboratory measurements | ||||
NT-proBNP* | −6.689 | <0.001‡ | ||
Serum albumin | 1.877 | 0.004‡ | ||
Total serum protein | −0.651 | 0.117 | ||
Creatinine clearance | 0.369 | <0.001‡ | 0.331 | <0.001‡ |
24-h Urinary albumin | 0.046 | 0.098 | ||
24-h Urinary sodium | 0.177 | <0.001‡ | 0.077 | 0.023‡ |
HbA1C | 2.422 | 0.356 | ||
Cholesterol | 1.547 | 0.315 | ||
HDL | −7.268 | 0.088 | ||
LDL | 1.930 | 0.271 | ||
Calcium | −21.940 | 0.257 | ||
PTH | −0.446 | 0.270 | ||
PRC* | −1.640 | 0.086 | ||
PRA* | −1.623 | 0.060 | ||
Aldosterone* | −4.281 | 0.032‡ | ||
1,25(OH)2D | 0.046 | 0.207 |
CHF, chronic heart failure; BMI; body mass index; HF, heart failure; NYHA, New York Heart Association; LVEF, left ventricular ejection fraction; ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; MRA, mineralocorticoid-receptor antagonists; NT-proBNP; NH2-terminal pro-B-type natriuretic peptide; HDL, high-density lipoprotein; LDL, low-density lipoprotein; PTH, parathyroid hormone; PRC, plasma renin concentration; PRA, plasma renin activity.
Skewed data, normalized by logarithmic transformation. ‡Significant P value.