Table 5.

Cox proportional hazards model of the association of sulfate clearance with disease outcome in CHF, adjusted for associated clinical parameter separately and in conjunction

	Sulfate Clearance
Model	HR* (95% CI)	P value
1: Crude	0.38 (0.23–0.63)	<0.001‡
2: Adjusted for diuretics use	0.42 (0.25–0.71)	0.001‡
3: Adjusted for diuretics use and creatinine clearance	0.71 (0.35–1.44)	0.344
4: Adjusted for diuretics use and 24-h urinary sodium	0.43 (0.25–0.75)	0.003‡
5: Adjusted for diuretics use, creatinine clearance and 24-h urinary sodium	0.72 (0.35–1.45)	0.354
6: Adjusted for creatinine clearance	0.59 (0.30–1.18)	0.140
7: Adjusted for creatinine clearance and 24-h urinary sodium	0.60 (0.30–1.19)	0.149
8: Adjusted for 24-h urinary sodium	0.39 (0.23–0.67)	0.001‡

HR per SD increase. CHF, chronic heart failure; HR, hazard ratio; CI, confidence interval. ‡Significant P value.