Table 3.
Hemodynamic parameters in infarcted animals
| BL (PreBSGS) | BSGS | BL (PreBMCGS) | BMCGS (PreCSD) | PreCSD | PostCSD | BL (PreMCGS PostCSD) | BMCGS (PostCSD) | |
|---|---|---|---|---|---|---|---|---|
| HR, bpm | 85 ± 10.7 | 94 ± 21* | 84 ± 11.8 | 112 ± 22*§ | 83 ± 13 | 84 ± 13 | 84 ± 13 | 114 ± 24* |
| dP/dtmax, mmHg/s | 1,246 ± 390 | 2,127 ± 315* | 1,123 ± 332 | 2271 ± 9678*† | 984 ± 349 | 880 ± 337 | 878 ± 338 | 1797 ± 937* |
| dP/dtmin, mmHg/s | −1,280 ± 582 | −1,157 ± 542 | −1,179 ± 537 | −1,093 ± 635 | −1,090 ± 571 | −1,025 ± 634 | −1,027 ± 630 | −958 ± 574 |
| LVESP, mmHg | 90 ± 20 | 123 ± 28 | 86 ± 21 | 99 ± 21§ | 78 ± 25 | 69 ± 22‡ | 69 ± 22 | 86 ± 26 |
Values represent mean ± SD % change in parameters from prestimulation value (n = 12). PostCSD values represent hemodynamic parameters after a 30-min period of stabilization after removal of stellate ganglia. PreCSD represents hemodynamic values immediately before removal of the stellate ganglia. HR, heart rate; dP/dtmax, dP/dtmin, maximum and minimum dP/dt; LVESP, left ventricular end-systolic pressure; BSGS, bilateral stellate ganglion stimulation; BMCGS, bilateral middle cervical ganglion stimulation.
P value < 0.05 for % change from baseline (prestimulation).
P = 0.06 for % increase in dP/dtmax with BMCGS compared with BSGS.
P = 0.02 for comparison of PreCSD vs. PostCSD.
P < 0.01 for comparison of BMCGS vs. BSGS.