Table 2.
Blood pressure parameters of male MasR+/+ and MasR−/− mice fed a LF or HF diet
|
MasR+/+ |
MasR−/− |
|||
|---|---|---|---|---|
| LF | HF | LF | HF | |
| 24 Hour | ||||
| Heart rate, beats/min | 571 ± 13 | 585 ± 8 | 550 ± 7 | 582 ± 10* |
| Activity, counts/min | 5.3 ± 1.2 | 4.2 ± 0.6 | 4.4 ± 0.7 | 4.0 ± 0.5 |
| PP, mmHg | 32.0 ± 2.1 | 36.3 ± 1.9 | 32.1 ± 1.3 | 38.6 ± 1.2* |
| Light | ||||
| SBP, mmHg | 115.7 ± 2.6 | 127.0 ± 1.0* | 114.8 ± 0.5 | 124.2 ± 1.1* |
| DBP, mmHg | 85.3 ± 3.3 | 92.1 ± 2.0* | 83.4 ± 0.5 | 87.0 ± 0.8 |
| MAP, mmHg | 100.8 ± 2.7 | 110.0 ± 1.3* | 99.3 ± 0.4 | 105.9 ± 0.8*# |
| Dark | ||||
| SBP, mmHg | 127.5 ± 1.8 | 137.0 ± 0.7* | 126.6 ± 1.3 | 132.7 ± 1.2*# |
| DBP, mmHg | 93.8 ± 2.4 | 99.1 ± 2.2 | 93.6 ± 0.7 | 92.5 ± 0.7 |
| MAP, mmHg | 110.9 ± 1.6 | 118.4 ± 1.2* | 110.5 ± 0.6 | 112.9 ± 0.8# |
Data are means ± SE; n = 5–9 mice/diet/genotype.
*
P < 0.05 compared with LF within genotype following pairwise statistical analysis.
#
P < 0.05 compared with MasR+/+ within diet group following pairwise statistical analysis.