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. 2016 Dec 23;312(3):H485–H500. doi: 10.1152/ajpheart.00035.2016

Fig. 7.

Fig. 7.

PECAM-1 is required for the FSS-induced production of PGI2 ECs. Cells were transfected with PECAM-1 siRNA 72 h before exposure to FSS. Experimental media were collected and assayed for PGI2 stable metabolite 6-keto-prostaglandin F1α. A: FSS-induced PGI2 production in BAECs treated with PECAM-1 siRNA (n = 4). B: FSS-induced PGI2 production in HUVECs treated with PECAM-1 siRNA (n = 4). Values are means ± SE. *P < 0.05 vs. untreated static (S) controls. #P < 0.05 vs. untreated flow (F) controls.