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. 2017 Mar 18;9(1):1–11. doi: 10.15171/jcvtr.2017.01

Table 3. Summary risk estimates of the association between dairy foods and risk of stroke .

N b No. of cases Risk estimate (95% CI) Heterogeneity test References
REM I 2 (%) P P a
Total dairy 19 29300 0.88(0.82-0.95) 63.1 0.00
Outcome 0.00
Incidence 8 13979 0.96(0.88-1.04) 49.7 0.05 [13, 15, 20, 21, 36, 43, 47, 49]
Mortality 11 15321 0.80(0.76-0.83) 0.00 0.66 [11, 16-18, 37, 41, 44, 45]
Location where the study was conducted
Europe 10 10985 0.96(0.89-1.04) 29.8 0.17 1 [11, 13, 20, 21, 36, 41, 45, 47, 49]
Asia 7 14109 0.79(0.75-0.82) 0.00 0.73 0.00 [16, 17, 37, 43, 44]
Others 2 4206 0.91(0.85-0.98) 0.00 0.68 0.57 [15, 18]
Sex 0.90
Male 7 9007 0.92(0.79-1.07) 68.5 0.00 [13, 15, 17, 36, 37, 41, 45]
Female 4 1021 0.78(0.66-0.91) 0.00 0.67 [17, 37, 41]
Quality
High 13 10343 0.89(0.85-0.94) 0.00 0.44 1 [11, 15, 17, 20, 21, 37, 41, 43, 44, 49]
Moderate 4 7731 1.01(0.84-1.21) 63.9 0.04 0.05 [13, 18, 36, 47]
Low 2 11226 0.79(0.75-0.83) 0.00 0.90 0.26 [16, 45]
Adjusting for 4 or more covariates (smoking, alcohol, total energy intake, BMI, physical activity and ≥3 other dietary variables) (0.10) a
Yes 14 16368 0.91(0.85-0.98) 49.1 0.02 [13, 15, 17, 18, 20, 36, 37, 41, 47, 49]
No 5 12932 0.79(0.75-0.83) 0.00 0.98 [11, 16, 43-45]
Fat content of dairy 0.62
Low fat 9 14689 0.94(0.90-0.98) 0.00 0.61 [13, 15, 18, 20, 41, 47, 49]
High fat 9 14689 0.95(0.91-1) 0.00 0.61 [13, 15, 18, 20, 41, 47, 49]

BMI: body mass index, REM: random effect model.

a P value for meta-regression, and location where the study was conducted (Europe as the reference) and Quality (high as the reference) and sex (male as the reference).

b N: number of results; 2 separate results (male and female) were available in 3 studies.17,37,41