Table 3. Adverse events at day 7 during the 1st, 2nd, 3rd and 4th cycle of chemotherapy.
| Adverse Event | Intervention group |
Control group |
P-value | ||||||
|---|---|---|---|---|---|---|---|---|---|
| n | Grade 0 | Grade 1 or 2 | Grade 3 or 4 | n | Grade 0 | Grade 1 or 2 | Grade 3 or 4 | ||
| 1st cycle | 128 | 129 | |||||||
| Pain | 114 (89.1%) | 14 (10.9%) | 0 | 107 (76.98%) | 32 (23.0%) | 0 | <0.05 | ||
| 2nd cycle | 120 | 124 | |||||||
| Hb | 77 (64.20%) | 16 (13.3%) | 27 (22.50%) | 107 (79.9%) | 11 (8.2%) | 16 (11.90%) | <0.05 | ||
| Bilirubin | 56 (46.7%) | 5 (4.2%) | 59 (49.20%) | 84 (55.1%) | 2 (2.8%) | 48 (42.1%) | <0.05 | ||
| Dry mouth | 104 (86.7%) | 15 (12.5%) | 0 | 97 (72.4%) | 37 (27.6%) | 0 | <0.01 | ||
| 3rd cycle | 114 | 126 | |||||||
| Vomiting | 84 (73.7%) | 27 (23.7%) | 2 (1.8%) | 71 (56.35%) | 55 (43.7%) | 0 | <0.01 | ||
| Diarrhea | 112 (98.2%) | 1 (0.9%) | 0 | 116 (92.10) | 10 (7.9%) | 0 | <0.05 | ||
| 4th cycle | 105 | 122 | |||||||
| Dry mouth | 93 (88.6%) | 10 (9.5%) | 0 | 99 (81.1%) | 23 (18.9%) | 0 | <0.05 | ||
Hb = Hemoglobin B.