Figure 2.

Neuronal differentiation in the sensory ganglia is not affected in Wnt1Cre/+;fnb/fnb;nbl^–/– mice. Differentiation of TrkA, TrkB, and parvalbumin-positive neurons in the DRG of control (A–C) and Wnt1Cre/+;fnb/fnb;nbl^–/– (E–G) mice at P0. (I) The total numbers of TrkA⁺ neurons were determined at the level of L1, TrkB⁺ neurons were determined at L2, and parvalbumin⁺ neurons were determined at the level of L3. (D,H,I) The number of sensory afferent axons in the dorsal roots of control (D) and conditional mutant (H) mice was not significantly different at the thoracic level. At least three animals are used for counting in each group. Numbers represent mean ± SEM.