Figure 5.

Endothelial nitric oxide synthase (eNOS) exists more in the monomeric form in the hearts of mice following exercise training.

Note: (A) Immunoblots of eNOS dimers and monomers. (B) Ratio of eNOS monomer to dimer. (C, D) Total superoxide (C) and nitric oxide synthase-dependent superoxide (D) production rates. Numbers inside bars indicates sample size. Values are expressed as the mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001. ###P < 0.001, vs. β₃-AR KO mice (β₃-AR). SED: Sedentary; Ex: exercise; RLU: relative light unit; WT: Wild-type mice.