Table 3.

Heritability estimates for BMI and regional GMV

Variable	Heritability (95% CI Bounds)	pACE
BMI	0.73 (0.35 – 1.10)	0.0002
Regional GMV [MNIxyzmm]
L Cerebellum [−14 −73 −48]	0.82 (0.75 – 0.88)	<0.0001
R Cerebellum [17 −75 −47]	0.79 (0.48 – 1.10)	<0.0001
R Midbrain [8 −15 −5]	0.77 (0.69 – 0.86)	<0.0001
R Amygdala [−30 −3 −18]	0.74 (0.36 – 1.13)	0.0002
L Putamen [−33 −4 3]	0.71 (0.61 – 0.81)	<0.0001
L Midbrain [−5 −12 −3]	0.70 (0.60 – 0.81)	<0.0001
L Amygdala [−30 −3 −20]	0.68 (0.36 – 1.13)	0.0008
L Nucleus Accumbens [−11 6 −8]	0.65 (0.54 – 0.77)	<0.0001
R Orbitofrontal Cortex [9 53 −26]	0.57 (0.13 – 1.01)	0.01
L Orbitofrontal Cortex [−42 48 −14]	0.56 (0.13 – 1.00)	0.01
R Parahippocampal Gyrus [23 −37 −8]	0.56 (0.10 – 1.02)	0.02
R Ventromedial Prefrontal Cortex [2 21 −26]	0.54 (0.13 – 0.94)	0.01
L Parahippocampal Gyrus [−21 −37 −11]	0.51 (0.04 – 0.98)	0.03
L Insula [−44 −19 3]	0.50 (0.06 – 0.94)	0.03
R Insula [39 −19 −8]	0.45 (0.06 – 0.83)	0.02
R Middle Temporal Gyrus [63 −43 3]	0.42 (−0.06 – 0.89)	0.08
R Anterior Cingulate [8 54 10]	0.38 (−0.16 – 0.92)	0.16
L Anterior Cingulate [−9 53 −2]	0.22 (−0.31 – 0.75)	0.41
L Inferior Temporal Gyrus [−32 −3 −50]	0.21 (−0.13 – 0.55)	0.22

Heritability estimates (ACE model) for BMI and regional GMV of selected ROIs with corresponding 95% confidence intervals. The respective peak location for each ROI is specified in squared brackets. MNI: Montreal Neurological Institute.