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. 2017 Apr 24;7:46654. doi: 10.1038/srep46654

Figure 4. Effects of flumazenil on the modulation of GABA response by curcumol, menthol, or DZP in cultured hippocampal neurons.

Figure 4

(a, c, e) Representative current traces induced by GABA (1 μM) alone, or in the absence or presence of curcumol (100 μM, a), or menthol (300 μM, c), or DZP (1 μM, e), or in the simultaneous presence of flumazenil (1 μM). (b, d, f) Pooled data from (a), (c) and (e), respectively. Data represent peak current amplitude normalized to that induced by GABA (1 μM) alone (dashed line). n = 5–13 each group. N.S., not significant, *P < 0.05, **P < 0.01, ***P < 0.001, compared with GABA (1 μM) alone (dashed line), paired Student’s t-test; N.S., not significant, ###P < 0.001, compared as indicated, unpaired Student’s t-test.