Fig. 4.

AFB₁-induced carcinogenesis in Neil1^−/− and XPA^−/− mice. (A) The individual diameter of liver tumors observed in AFB₁-injected WT and Neil1^−/− mice. Relative AFB₁-induced tumor risk analysis in (B) Neil1^−/− mice, with data illustrated by blue and red symbols representing AFB₁ doses of 1.0 and 7.5 mg/kg respectively, and (C) XPA^−/− mice, with data illustrated by green, blue, and red symbols representing AFB₁ doses of 0, 0.6, and 1.5 mg/kg, respectively.