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New interventions and their targets of myocardial fibtosis.
| New interventions | Targets | Mechanisms |
|---|---|---|
| DRUG | ||
| Serelaxin | Relaxin 2 | Inhibit the activation of fibroblasts and collagen collagen production |
| AntimiR-21 | miRNA-21 | Reduces interstitial fibrosis and attenuates cardiac dysfunction |
| AntimiR-208a | miR-208a | Suppress fibrosis |
| MMPs inhibitor | MMPs | Inhibit pathological cardiac remodeling |
| MECHANOTHERAPY | ||
| CRT | Reverse remodeling | |
