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. 2017 Apr 20;19(5):421–428. doi: 10.1016/j.neo.2017.03.003

Figure 2.

Figure 2

TuKO of fgfr1 in the PyMT-induced mammary tumors. (A) Scheme of infecting mammary glands of K19-tva/fgfr1loxP/loxP mice and control K19-tva mice using the RCI-PyMT viruses through intraductal injections. (B) PCR for fgfr1KO-specific alleles confirms TuKO of fgfr1 in RCI-PyMT viruses–infected K19-tva/fgfr1loxP/loxP mice. (C) Western blots for the expression of FGFR1 and E-cadherin in tumors. Western blot for β-actin and Ponceau S staining of membrane are shown as loading control. One tumor expressed little β-actin. MW: molecular weight marker.