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. 2017 Apr 20;19(5):421–428. doi: 10.1016/j.neo.2017.03.003

Figure 3.

Figure 3

TuKO of fgfr1 in the PyMT-induced mammary tumors significantly extends host mouse survival. (A) Knockout of fgfr1 in the PyMT-induced mammary tumors significantly extends hosts survival (P = .0029 for log-rank test, and P = .0033 for Gehan-Breslow-Wilcoxon test). (B) Mammary tumor weights were comparable between fgfr1 TuKO tumors and control tumors at the end of this survival study (P = .92, unpaired t test). (C) Histopathology of representative fgfr1 TuKO and control mammary tumors. (D) Immunofluorescence staining of E-cadherin on representative fgfr1 TuKO and control mammary tumors.