Table 1.

Comparison of measurements between baseline and follow-up within categories of Body Mass Index (BMI).

	Normal (BMI < 25)				Overweight (BMI = 25–30)				Obese (BMI ≥ 30)
	N	Baseline	Follow-up	Baseline vs. Follow-up	N	Baseline	Follow-up	Baseline vs. Follow-up	N	Baseline	Follow-up	Baseline vs. Follow-up
BMI (kg/m2)	1398	22.4 ± 1.9	22.9 ± 2.5	<0.001	1437	27.3 ± 1.4	27.6 ± 1.9	<0.001	1047	34.4 ± 4	34.5 ± 4.4	0.02
Vitamin D dose (IU/d)	1225	2232 ± 2463	6090 ± 3221	<0.001	1246	2111 ± 2391	6751 ± 3520	<0.001	928	1932 ± 2578	7652 ± 4026	<0.001
Serum 25(OH)D (nmol/L)	1366	91.5 ± 29	131 ± 40	<0.001	1446	87.2 ± 28	126 ± 38	<0.001	1053	80 ± 26	118 ± 38	<0.001
Serum Calcium (mmol/L)	1350	2.40 ± 0.08	2.39 ± 0.08	0.08	1413	2.40 ± 0.09	2.39 ± 0.09	0.3	1045	2.39 ± 0.09	2.39 ± 0.09	0.2
Serum PTH (ng/L)	453	35.7 ± 14	35.2 ± 14	0.4	494	37.8 ± 14	36.6 ± 14.5	0.06	327	41.9 ± 16.4	39.3 ± 15	0.001
Serum hs-CRP (mg/L)	1122	1.10 ± 1.4	1.33 ± 1.4	<0.001	1155	1.63 ± 1.7	1.86 ± 1.6	<0.001	773	2.68 ± 2.2	2.86 ± 2.2	<0.001
Serum Creatinine (µmol/L)	1193	77.6 ± 18.7	78.2 ± 16.7	<0.001	1243	82 ± 19	82.8 ± 20	0.01	915	82.5 ± 32	81.9 ± 23	0.8
Estimated GFR (mL/min)	1193	78.5 ± 20	76.7 ± 18	<0.001	1243	75.6 ± 16.7	74.5 ± 17.3	<0.001	915	75 ± 17.5	74.7 ± 17.5	0.1
Serum ALT (U/L)	1191	20.6 ± 16.6	18.3 ± 11	<0.001	1246	24.7 ± 19.3	22.2 ± 15.8	<0.001	907	27.3 ± 22	24.5 ± 16	<0.001
Serum GGT (U/L)	1191	24.7 ± 37.6	20.6 ± 20.8	<0.001	1246	30.7 ± 36	27.5 ± 31.6	<0.001	907	35.4 ± 28	31.6 ± 29	<0.001
Urine Calcium: Creatinine Ratio (mg/mg)	190	0.124 ± 0.08	0.131 ± 0.08	0.2	193	0.108 ± 0.07	0.129 ± 0.07	<0.001	135	0.096 ± 0.07	0.111 ± 0.07	0.01

PTH: Parathyroid hormone; hs-CRP: high-sensitivity C reactive protein; GFR: Glomerular filtration rate; ALT: Alanine aminotransferase; GGT: Gamma glutamyltransferase