Figure 4.
Circadian rhythm of arterial blood glucose (mg/mL) concentrations in rats that underwent isoflurane anesthesia (blue) compared with brief CO2 anesthesia (amber). Black bars represent the dark phase; all values differed significantly (P < 0.05) between groups at each time point. Values are double plotted. The total numbers of samples at time points 0400, 0800, 1200, 1600, 2000, and 2400 were 6 in all cases for the isoflurane group and 11, 12, 12, 12, 12, and 12 for the CO2 group, respectively. For reference, the gray line represents the vendor-reported mean values in Sprague–Dawley rats.30