Figure 6.
Circadian rhythm of arterial blood lactate (mmol/L) concentrations in rats that underwent isoflurane anesthesia (blue) compared with brief CO2 anesthesia (amber). Black bars represent the dark phase; *, significant (P < 0.05) difference between groups. Values are double plotted to show rhythmicity. The total numbers of samples at time points 0400, 0800, 1200, 1600, 2000, and 2400 were 4, 6, 6, 6, 6, and 6 for the isoflurane group and 11, 12, 12, 12, 12, 12 for the CO2 group, respectively. For reference, the gray line represents the mean value reported in Sprague–Dawley rats.34