Table 2.
Enrichment in Gene Ontology categories for stable and variable gene deserts
| Category | Enrichment | Classification |
|---|---|---|
| Stable gene deserts | ||
| Regulation of metabolism | 4.4 | biological process |
| Transcription factor activity | 4.2 | molecular function |
| Transcription coactivator activity | 4.0 | molecular function |
| Regulation of biosynthesis | 3.8 | biological process |
| Transcription regulator activity | 3.6 | molecular function |
| Transcription factor binding | 3.2 | molecular function |
| DNA binding | 2.8 | molecular function |
| Regulation of transcription | 2.8 | biological process |
| Transcription | 2.7 | biological process |
| Development | 2.0 | biological process |
| Variable gene deserts | ||
| Glutamate receptor activity | 7.8 | molecular function |
| Inotropic glutamate receptor activity | 7.7 | molecular function |
| Amine receptor activity | 6.2 | molecular function |
| Sulfotransferase activity | 4.2 | molecular function |
| Cell adhesion | 3.0 | biological process |
| Transmission of nerve impulse | 2.8 | biological process |
| Neuromuscular physiological process | 2.8 | biological process |
| Synaptic transmission | 2.7 | biological process |
| Calcium ion binding | 2.2 | molecular function |
| Organogenesis | 1.9 | biological process |
| Morphogenesis | 1.7 | biological process |
| Development | 1.7 | biological process |
| Cell communication | 1.6 | biological process |
The statistical significance of the reported numbers is supported by the P-values <10-5 as quantified in a comparison with the purely-by-chance expectations.