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Inhibition (IC50 values) of 7-ethoxyresorufin O-deethylation (EROD) activities of CYP1B1 (A), 1A2, (B), and 1A1 (C) by PAHs, PAH metabolites, Trp-P-1 and Trp-P-2, and flavonoids and acetylenic PAHs. IC50 values exceeded over 1.0 μM are indicated in the figure. Data are taken from Shimada and Guengerich (20) with modification.
