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. 2017 Apr 13;11:1221–1231. doi: 10.2147/DDDT.S127568

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© 2017 Lim and Bolster. This work is published and licensed by Dove Medical Press Limited

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Changes in the levels of bone formation markers and bone resorption markers with subcutaneous injections of TPTD (20 μg daily) or ROMO (210 mg once monthly) for 1 year.

Notes: Reproduced from Appelman-Dijkstra NM, Papapoulos SE. Modulating bone resorption and bone formation in opposite directions in the treatment of postmenopausal osteoporosis. Drugs. 2015;75(10):1049–105836 which was originally sourced from Leder BZ, Tsai JN, Uihlein AV, et al, Two years of Denosumab and teriparatide administration in postmenopausal women with osteoporosis (The DATA Extension Study): a randomized controlled trial, J Clin Endocrinol Metab, 2014;99(5):1694–1700, by permission of Oxford University Press.49

Abbreviations: ROMO, romosozumab; TPTD, teriparatide.