Table 1.
Sociodemographic, clinical, and functional characteristics of the patients included in different studies
| Parameter | All# n=5,969 | INSEPOC n=2,026 | FYCEPOC n=2,735 | NEREA n=622 | DEPREPOC n=586 |
|---|---|---|---|---|---|
| Age (years) | 67.5 (9.6) | 67.4 (9.6) | 67.0 (9.6) | 68.8 (10.0) | 68.8 (9.1) |
| Sex (male) | 5,145 (86.3) | 1,831 (90.4) | 2,273 (83.1) | 546 (87.9) | 495 (85.1) |
| Active smokers | 1,394 (23.4) | 534 (26.5) | 616 (23.7) | 126 (20.7) | 118 (20.31) |
| Body mass index (kg/m2) | 27.8 (4.4) | 27.9 (4.4) | 27.7 (4.3) | 27.7 (4.1) | 27.5 (4.6) |
| Comorbidities (Charlson index) | 2 (1–3) | 2 (1–3) | 2 (1–2) | 2 (1–3) | 2 (1–3) |
| mMRC (n=3,937) | |||||
| 0 | 246 (6.3) | – | 170 (6.2) | 51 (8.3) | 25 (4.2) |
| 1 | 1533 (38.9) | – | 1,027 (37.5) | 299 (48.4) | 207 (35.4) |
| 2 | 1373 (34.9) | – | 987 (36.1) | 159 (25.8) | 227 (38.8) |
| 3 | 665 (16.9) | – | 459 (16.8) | 88 (14.3) | 118 (20.2) |
| 4 | 120 (3.0) | – | 92 (3.4) | 20 (3.2) | 8 (1.4) |
| Ambulatory COPD exacerbation¶ | 1 (0–2) | 2 (1–3) | 1 (0–2) | 1 (1–2) | 2 (1–3) |
| COPD admissions¶ | 0 (0–1) | 0 (0–1) | 0 (0–1) | 0 (0–1) | 1 (0–2) |
| FEV1 (% predicted) | 50.7 (17.2) | 47.7 (16.2) | 51.9 (17.9) | 52.8 (15.9) | 52.8 (16.7) |
| FEV1 levels | |||||
| ≧80% predicted | 319 (5.3) | 71 (3.5) | 201 (7.4) | 18 (2.9) | 29 (4.9) |
| ≧50% and <80% predicted | 2,634 (44.1) | 784 (38.7) | 1,225 (44.8) | 325 (52.3) | 300 (51.2) |
| ≧30% and <50% predicted | 2,315 (38.8) | 878 (43.3) | 1,002 (36.6) | 226 (36.3) | 209 (35.7) |
| <30% predicted | 701 (11.7) | 293 (14.5) | 307 (11.2) | 53 (8.5) | 48 (8.2) |
| GOLD groups (n=3,209) | |||||
| A | 156 (4.9) | – | 141 (5.3) | – | 15 (2.8) |
| B | 542 (16.9) | – | 491 (18.3) | – | 51 (9.7) |
| C | 168 (5.2) | – | 146 (5.5) | – | 22 (4.2) |
| D | 2,343 (73.0) | – | 1,903 (70.9) | – | 440 (83.3) |
| BODEx index (n=3,765) | 2 (1–4) | – | 2 (1–4) | 2 (1–4) | 3 (2–4) |
| CAT (n=3,262) | 20.0 (8.3) | – | 19.2 (8.2) | – | 21.2 (8.1) |
Notes: Data are presented as n (%), mean (SD), or median (percentile 25–p75).
Some variables have missing values: 27 in age, 9 in sex, 169 in active smoker, 54 in body mass index, 165 in ambulatory COPD exacerbation, and 135 in COPD admissions.
Number of events in the previous 12 months.
Abbreviations: BODEx, body mass index, airway obstruction, dyspnea, exacerbation; CAT, COPD assessment test; DEPREPOC, Depression in patients with COPD; FEV1, forced expiratory volume in the first second; FYCEPOC, Phenotypes and quality of life of patients with COPD; GOLD, Global Initiative for Chronic Obstructive Lung Disease; INSEPOC, Impact of socio-economic status on quality of life of COPD patients; mMRC, modified Medical Research Council dyspnea score; NEREA, New severity scale for COPD in primary care; SD, standard deviation.