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. 2017 Apr 10;13(4):e1005485. doi: 10.1371/journal.pcbi.1005485

Fig 7. Biological case studies.

Fig 7

A: β-catenin in complex with TCF7L2. Green: native TCF7L2; orange: rank 1 model of TCF7L2; fnat 0.38, I-RMSD 2.85 Å, L-RMSD 7.94 Å. PDB ID: 1jpw. B-E: Human and mouse Cbp/p300 TAZ1 domain in complex with CITED2 and Hif-1α. Green/cyan: native CITED2/Hif-1α; orange/yellow: model CITED2/Hif-1α. Ball and stick: LPXL motif. B-C: Human TAZ1 and CITED2. B: bound (1p4qB); rank 5 model; fnat 0.27, I-RMSD: 4.2 Å, L-RMSD: 7.6 Å. C: unbound (1l3eB); rank 9 model; fnat 0.17, I-RMSD: 7.1 Å, L-RMSD: 9.6 Å. D-E: Mouse TAZ1 and Hif-1α. D: bound (1l8cA); rank 16 model; fnat 0.05, I-RMSD 11.7 Å, L-RMSD 20.1 Å. E: unbound (1u2nA); rank 9 model; fnat 0.20, I-RMSD 6.4 Å, L-RMSD 10.4 Å. F: Unbound complex between BoNT/A and sn2. Green: native sn2; orange: rank 1 model of sn2; fnat 0.00, I-RMSD 15.7 Å, L-RMSD 38.2 Å. Receptor PDB ID 1xtfA (unbound).