Table 4. Secondary structure prediction accuracy.

Method	Accuracy
JPred	66.4%
Porter	81.2%
PSIPRED	69.7%
SSpro	75.4%
All	57.0%
Best	86.1%

Accuracy: percentage of all residues correctly predicted. Secondary structure classes were assigned using DSSP [48]. DSSP classes GHI are considered H, EB are considered E, and all others are considered C. All: all four methods predict the correct class. Best: at least one of the four methods predicts the correct class. Computed using 1ycrB, 1fv1C, 1wkwB, 2cpkI, 1sb0B, 1sqkB, 2bzwB, 3owtC, 1devB, 1l8cB, and 1xtgB.