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. 2017 Apr 18;10:915–925. doi: 10.2147/JPR.S125045

Figure 4.

Figure 4

Histological analysis of tumor xenografts in bone represented by hematoxylin and eosin staining.

Notes: (A) Sham-injected mice. Tumor-injected mice show extensive invasion of xenograft into the femur with destruction of growth plate (B, D) and in some cases breaching of the periosteum (C). Arrowheads indicate tumor tissue.