Table 2. Descriptive characteristics of case-patients with invasive extrapulmonary NTM infections and control-patients among patients who underwent cardiothoracic surgery, York, Pennsylvania, USA, 2015*.
Characteristic |
Case-patients, n = 11 |
Control-patients, n = 48 |
p value† |
Demographics | |||
Age, y, mean (range) | 69 (47–84) | 64 (20–84) | 0.33 |
Male sex | 9 (82) | 27 (56) | 0.17 |
White race |
11 (100) |
45 (94) |
1.00 |
Predisposing medical condition | |||
Chronic lung disease | 4 (36) | 8 (17) | 0.21 |
COPD | 1 (9) | 8 (17) | 1.00 |
Sarcoidosis | 3 (27) | 0 | 0.005 |
Diabetes | 1 (9) | 15 (31) | 0.26 |
Immunocompromised | 3 (27) | 10 (21) | 0.69 |
HIV | 0 | 0 | NA |
Transplant | 0 | 0 | NA |
Chemotherapy | 2 (18) | 9 (19) | 1.00 |
Steroid treatment | 0 | 2 (4) | 1.00 |
Hematologic malignancy‡ | 2 (18) | 1 (2) | 0.09 |
*Values are no. (%) patients except as indicated. COPD, chronic obstructive pulmonary disease; NA, not applicable; NTM, nontuberculous mycobacteria. †Fisher exact test for categorical variables or two 2-sample t tests with pooled variance. ‡Among cases, hematologic malignancy included chronic lymphocytic leukemia and myelodysplastic syndrome. Among controls, hematologic malignancy included Hodgkin’s lymphoma.