Table 2.
Modified ICRS visual histological assessment scale
| Feature | Score |
|---|---|
| Hematoxylin and eosin | |
| Surface | |
| Smooth/continuous | 3 |
| Discontinuities/irregularities | 0 |
| Matrix | |
| Hyaline | 3 |
| Mixture: hyaline–fibrocartilage | 2 |
| Fibrocartilage | 1 |
| Fibrous tissue | 0 |
| Cell distribution | |
| Columnar | 3 |
| Mixed/columnar clusters | 2 |
| Clusters | 1 |
| Individual cells/disorganized | 0 |
| Cell-population viability | |
| Predominantly viable | 3 |
| Partially viable | 1 |
| <10% viable | 0 |
| Subchondral bone | |
| Normal | 3 |
| Increased remodeling | 2 |
| Bone necrosis/granulation tissue | 1 |
| Detached/fracture/callus at base | 0 |
| Cartilage mineralization (calcified cartilage) | |
| Normal | 3 |
| Abnormal/inappropriate location | 0 |
| Proliferating cell nuclear antigen | |
| Positive | 3 |
| Negative | 0 |
| Collagen type I | |
| Abundant | 3 |
| Little | 1 |
| None | 0 |
| Collagen type II | |
| Abundant | 3 |
| Little | 1 |
| None | 0 |
Abbreviation: ICRS, International Cartilage Repair Society.