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. 2017 Apr 19;10:2219–2226. doi: 10.2147/OTT.S130236

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© 2017 Lian et al. This work is published and licensed by Dove Medical Press Limited

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NVP-AUY922 inhibits the growth of PCC tumors.

Notes: (A) Tumor volume is shown in cubic milimeters, which is calculated as 0.5236× (length × width × height) in mice treated with either vehicle or NVP-AUY922 (35 mg/kg) for 15 days. (B) Representative images of tumor appearance after treatment with vehicle or NVP-AUY922. (C) Mean tumor weights of NVP-AUY922- and vehicle-treated mice. (D) Mean body weights of NVP-AUY922- and vehicle-treated mice. (E) Percentage of apoptotic cells in PC12 xenografts of NVP-AUY922- and vehicle-treated mice. *P<0.05 and **P<0.01.

Abbreviations: PCC, pheochromocytoma; CTR, control.