Figure 6.

EPCs were transfected with miR-138 mimic or miR-138 inhibitor, and cultured under normoxia or hypoxia for 24 h. (A) Reverse transcription-quantitative polymerase chain reaction and (B) western blotting analysis were performed to examine the levels of HIF-1α mRNA and protein, respectively. GAPDH was used as an internal reference. **P<0.01 vs. normoxia; ^#P<0.01 vs. hypoxia. EPC, endothelial progenitor cells; miR-NC, scramble miR mimics; HIF-1α, hypoxia-inducible factor 1α; miR, microRNA.