Table IV.
Differentially-expressed miRNAs in cervical cancer and their targets.
| miRNAs | P-value | Log FC | Target genes |
|---|---|---|---|
| miR-203 | 4.76×10−5 | 2.73 | TOP2A, PRC1, CXCL14, CRISP3, ID4, RRM2, TYMS, NDN, ESR1, SMC4 |
| miR-370 | 7.32×10−4 | 2.62 | AURKA, ESR1, CRCT1 |
| miR-638 | 8.63×10−5 | 2.16 | CXCL9, ESR1 |
| miR-494 | 6.72×10−4 | 1.80 | ESR1, PLOD2, CXCL14, MAL |
| miR-575 | 5.54×10−4 | 1.69 | ESR1, SMC4, EDN3, CXCL9, CYP2B6, CDKN2A |
| miR-125b | 1.42×10−5 | 1.67 | ESR1, RRM2, SPRR3, CDKN2A |
| miR-99a | 8.47×10−4 | 1.41 | ESR1 |
| miR-572 | 1.6×10−3 | 1.31 | CRCT1 |
| miR-375 | 7.39×10−6 | 1.19 | TYMS |
| miR-193b | 1.09×10−3 | 1.06 | CXCL14, ESR1 |
| miR-188 | 5.91×10−3 | 1.01 | ESR1, MMP1, ID4 |
| miR-106b | 6.91×10−8 | −1.07 | ESR1, CXCL14, CENPA, RRM2, CDKN2A, NDN, CRCT1 |
| miR-15b | 2.87×10−4 | −1.16 | ESR1, CXCL10, MAL, EDN3, CENPA |
| miR-16 | 1.39×10−4 | −1.22 | ESR1, CXCL10, EDN3, CENPA, ID4, PPP1R3C |
| miR-21 | 6.34×10−6 | −2.51 | CXCL14, EDN3, ESR1, NUSAP1 |
A positive log FC value represents the downregulation of that miRNA in cervical cancer, whilst a negative log FC value represents the upregulation of that miRNA in cervical cancer. Target gene names were listed according to the gene database at national center for biological information. miRNA/miR, microRNA; FC, fold-change.