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. 2017 Mar 22;50(5):1501–1512. doi: 10.3892/ijo.2017.3927

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Copyright: © Huang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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FGF7 promotes invasion and migration in human gastric cancer cells. (A–D) Invasion and migration assays showed the effect of FGF7 on invasion and migration in SGC7901 and MKN28 cells. The cells were photographed under an inverted microscope (magnification, ×200) (A and C). Number of cells was counted in three randomly chosen fields (B and D). (E) Schematic representation of the lentiviral vector used in transfection. (F) Western blot analysis for FGFR2 in transfected cells and SGC7901. (G) The relative expression of FGFR2 mRNA in transfected cells and SGC7901 as detected by qRT-PCR. (H and I) Cell invasion and migration assays of shRNA-2 and shRNA-NC transfected cells treated with FGF7 (10 ng/ml, 24 h). Data are presented as the mean ± SD of three independent experiments (^**P<0.01).