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RECK promoter hypermethylation was observed in ESCC patients. (A) The mean MI of the RECK promoter in ESCC and corresponding non-tumor tissues. (B) The RECK MI showed a decreasing trend in non-tumor tissues compared with ESCC tissues. Statistical analyses were performed using the paired t-test. RECK, reversion-inducing cysteine-rich protein with kazal motif; MI, methylation index; ESCC, esophageal squamous cell carcinoma.
