Table II.

Correlation of clinicopathological variables with RECK mRNA expression in esophageal squamous cell carcinoma.

Variable	n	−ΔΔCqRECK >0 (n=130)	−ΔΔCqRECK ≤0 (n=180)	Odds ratio (95% CI)	P-valuea
Gender					0.292
Male	180	80	100	1.28 (0.81–2.03)
Female	130	50	80
Age (years)					0.221
≥60	170	66	104	0.75 (0.48–1.19)
<60	140	64	76
Size (cm)					0.012
<3	172	83	89	1.81 (1.14–2.87)
≥3	138	47	91
Tobacco					0.571
Yes	168	68	100	0.88 (0.59–1.38)
No	142	62	80
Alcohol					1.000
Yes	147	65	82	1.0 (0.64–1.56)
No	163	65	98
Depth of invasion					0.296
T1–2	224	98	126	1.31 (0.79–2.19)
T3–4	86	32	54
AJCC stage					0.545
I–II	125	55	70	1.15 (0.73–1.82)
III–IV	185	75	110
Lymph node metastasis					<0.0001b
N0–1	148	85	67	3.19 (1.99–5.10)
N2–3	162	45	113
Distant metastasis					0.421
M0	251	108	143	1.27 (0.71–2.28)
M1	59	22	37
Differentiation					0.533
G1	88	36	52
G2	142	64	78
G3	80	30	50

^aComparisons were performed using Pearson's χ² test.

^bP<0.05. RECK, reversion-inducing cysteine-rich protein with kazal motif; MI, methylation index; CI, confidence interval; AJCC, American Joint Committee on Cancer.