Table III.

Correlation between TRIM28 expression and the clinicopathological characteristics of patients with breast cancer in GSE3494.

		TRIM28 expression
Clinicopathological characteristic	Number of patients	High	Low	Pearson's χ2 value	P-value
Age (years old)				0.346	0.557
≤50	55	20	35
>50	196	63	133
TP53 mutation status				9.771	0.002
Positive	58	29	29
Negative	193	54	139
ER expression status				1.954	0.162
Positive	213	68	145
Negative	34	15	19
PR expression status				5.997	0.014
Positive	190	55	135
Negative	61	28	33
Elston grade				14.200	0.001
I	67	13	54
II	128	42	86
III	54	28	26
Tumor size (cm)				2.654	0.103
<2	112	31	81
≥2	139	52	87
Lymph node metastasis				0.410	0.522
Yes	84	30	54
No	158	50	108

The top 1/3 of patients with the highest TRIM28 expression were defined as the high-expression group and the bottom 2/3 were defined as the low-expression group. P-values were obtained through the Pearson chi-square test for the comparison of the two groups (high vs. low) in different clinicopathological characteristics of patients with BC. ER, estrogen receptor; PR, progesterone receptor; TRIM28, tripartite motif containing 28; TP53, tumor protein p53.