Patient absolute neutrophil counts (black line) and platelets (grey line) during the follow-up. Dotted arrow indicates all-trans retinoic acid treatment, including induction, consolidation and maintenance. Cross symbol represents grade 2 infections. ANC, absolute neutrophil counts; BM, bone marrow; APL, acute promyelocytic leukemia; LGL, large granular lymphocyte; PB, peripheral blood; ATRA, all-trans retinoic acid; PLT, platelet; I, induction chemotherapy; C, consolidation chemotherapy.