(A) Bone marrow histology at large granular lymphocyte diagnosis: Increased CD3+ CD57+ lymphoid infiltrate, both interstitial and intra-sinusoidal, in the context of normally proliferating bone marrow, with cells at all differentiating stages. Magnification, ×200. (B) Bone marrow histology at acute promyelocytic leukemia diagnosis: CD3+ CD57+ lymphoid infiltrate, both interstitial and intra-sinusoidal, in the context of CD13+ CD33+ CD38+ CD64+ CD117+ CD14− CD34− human leukocyte antigen-antigen D related− CD11a-b− promyelo-blast marrow invasion. Magnification, ×100 (insert, ×200). CD, cluster of differentiation.