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. 2017 Feb 28;13(4):2531–2538. doi: 10.3892/ol.2017.5784

Table III.

Predictors of OS in patients with pancreatic ductal adenocarcinoma after resection.

OS (univariate) OS (multivariate)


Variable Number Median ± SE 95% CI Pa RR 95% CI Pb
Gender 0.006 0.920
  Male   85 13.00±1.35 10.36–15.64 1.036 0.520–2.064
  Female   54 18.90±6.99 5.20–32.60 1
Age (years) 0.842 0.613
  ≥65   43 12.30±3.85 4.75–19.85 1.193 0.603–2.358
  <65   95 13.20±1.21 10.84–15.56 1
Tumor location 0.337 0.087
  Head   79 13.70±2.85 8.12–19.29 1.699 0.926–3.119
  Non-head   54 11.00±1.85 7.38–14.62 1
Tumor size (cm) 0.662 0.721
  ≥4   98 13.00±2.43 8.24–17.76 1.119 0.605–2.070
  <4   39 15.00±3.08 8.97–21.03 1
Histological grade 0.535 0.284
  G3–4 106 13.00±2.68 7.74–18.26 1.493 0.717–3.106
  G1–2   19 14.30±2.35 9.70–18.90 1
T stage 0.060 0.051
  T3   81 12.50±1.16 10.24–14.76 1.783 0.988–3.185
  T1–2   56 16.80±2.99 10.93–22.76 1
N stage 0.004 0.189
  N1   78 11.00±1.06 8.93–13.27 1.468 0.827–2.611
  N0   54 18.90±2.92 13.56–24.24 1
PNI 0.409 0.245
  Present   69 12.70±1.53 9.70–15.70 1.456 0.773–2.739
  Absent   31 17.40±4.14 9.28–25.52 1
Nuclear WTAP expression 0.000 0.039
  High   45 11.00±1.54 7.98–14.02 1.855 1.033–3.333
  Low   83 18.80±3.09 12.75–24.85 1
Cytoplasmic WTAP expression 0.256 0.876
  High   53 17.00±5.20 6.81–27.19 1.054 0.541–2.056
  Low   75 12.70±1.43 9.90–15.50 1
a

Log-rank test

b

Multivariate Cox regression test. Total patient number does not equal 145 in all categories, as patient information was not available for all cases. OS, overall survival; SE, standard error; RR, relative risk; CI, confidence interval; G1, well-differentiated; G2, moderately-differentiated; G3, poorly-differentiated; G4, undifferentiated; T, tumor; N, lymph node; PNI, perineural invasion; WTAP, Wilms tumor 1-associated protein; 95% CI, 95% confidence interval; P, P-value.