Table III.
OS (univariate) | OS (multivariate) | ||||||
---|---|---|---|---|---|---|---|
Variable | Number | Median ± SE | 95% CI | Pa | RR | 95% CI | Pb |
Gender | 0.006 | 0.920 | |||||
Male | 85 | 13.00±1.35 | 10.36–15.64 | 1.036 | 0.520–2.064 | ||
Female | 54 | 18.90±6.99 | 5.20–32.60 | 1 | |||
Age (years) | 0.842 | 0.613 | |||||
≥65 | 43 | 12.30±3.85 | 4.75–19.85 | 1.193 | 0.603–2.358 | ||
<65 | 95 | 13.20±1.21 | 10.84–15.56 | 1 | |||
Tumor location | 0.337 | 0.087 | |||||
Head | 79 | 13.70±2.85 | 8.12–19.29 | 1.699 | 0.926–3.119 | ||
Non-head | 54 | 11.00±1.85 | 7.38–14.62 | 1 | |||
Tumor size (cm) | 0.662 | 0.721 | |||||
≥4 | 98 | 13.00±2.43 | 8.24–17.76 | 1.119 | 0.605–2.070 | ||
<4 | 39 | 15.00±3.08 | 8.97–21.03 | 1 | |||
Histological grade | 0.535 | 0.284 | |||||
G3–4 | 106 | 13.00±2.68 | 7.74–18.26 | 1.493 | 0.717–3.106 | ||
G1–2 | 19 | 14.30±2.35 | 9.70–18.90 | 1 | |||
T stage | 0.060 | 0.051 | |||||
T3 | 81 | 12.50±1.16 | 10.24–14.76 | 1.783 | 0.988–3.185 | ||
T1–2 | 56 | 16.80±2.99 | 10.93–22.76 | 1 | |||
N stage | 0.004 | 0.189 | |||||
N1 | 78 | 11.00±1.06 | 8.93–13.27 | 1.468 | 0.827–2.611 | ||
N0 | 54 | 18.90±2.92 | 13.56–24.24 | 1 | |||
PNI | 0.409 | 0.245 | |||||
Present | 69 | 12.70±1.53 | 9.70–15.70 | 1.456 | 0.773–2.739 | ||
Absent | 31 | 17.40±4.14 | 9.28–25.52 | 1 | |||
Nuclear WTAP expression | 0.000 | 0.039 | |||||
High | 45 | 11.00±1.54 | 7.98–14.02 | 1.855 | 1.033–3.333 | ||
Low | 83 | 18.80±3.09 | 12.75–24.85 | 1 | |||
Cytoplasmic WTAP expression | 0.256 | 0.876 | |||||
High | 53 | 17.00±5.20 | 6.81–27.19 | 1.054 | 0.541–2.056 | ||
Low | 75 | 12.70±1.43 | 9.90–15.50 | 1 |
Log-rank test
Multivariate Cox regression test. Total patient number does not equal 145 in all categories, as patient information was not available for all cases. OS, overall survival; SE, standard error; RR, relative risk; CI, confidence interval; G1, well-differentiated; G2, moderately-differentiated; G3, poorly-differentiated; G4, undifferentiated; T, tumor; N, lymph node; PNI, perineural invasion; WTAP, Wilms tumor 1-associated protein; 95% CI, 95% confidence interval; P, P-value.