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. 2017 Feb 7;13(4):2089–2096. doi: 10.3892/ol.2017.5691

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Copyright: © Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Kaplan-Meier curves of the low-risk and high-risk subgroups defined by the irinotecan-resistance and oxaliplatin-resistance gene signatures. (A) Irinotecan-resistance signature. (B) Oxaliplatin-resistance signature. The GSE17536 dataset's (C) irinotecan- and (D) oxaliplatin-resistance signatures. The GSE17537 dataset's (E) irinotecan- and (F) oxaliplatin-resistance signatures. These two gene signatures were able to stratify patients with colorectal cancer into low- and high-risk subgroups with significant differences in terms of the prognosis in the GSE14333 training dataset.