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. 2017 Feb 21;13(4):2723–2730. doi: 10.3892/ol.2017.5754

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Tumor samples were harvested for (A) histological analysis (H&E and survivin staining), (B) RT-qPCR and (C) western blot analysis of survivin expression levels following survivin siRNA nanoliposome treatment. The mRNA expression levels of survivin are measured relative to GAPDH (magnification ×40). ***P<0.001, vs. the NC-IV group. H&E, hematoxylin and eosin; IHC, immuohistochemistry; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; siRNA, small interfering RNA; NC-IV, negative control small interfering RNA administered intravenously; DOX, intraperiotoneal injection of doxorubicin hydrochloride; SU-IV, intravenous injection of survivin small interfering RNA nanoliposome; SU-IT, intratumoral injection of survivin small interfering RNA nanoliposome.