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. Author manuscript; available in PMC: 2017 Apr 24.
Published in final edited form as: Nano Lett. 2016 Mar 23;16(4):2198–2204. doi: 10.1021/acs.nanolett.5b04364

Figure 3.

Figure 3

IMP compatibility with plate readers. A. Expansion index and supernatant IL-2 from T cells activated on grating geometries; B. ELISA IL-2 measurements from a well plate with 96 samples of four donors and four different topographies tested; C. Expansion index and supernatant IL-2 from T cells activated on grid topographies after 2–3 days culturing; D. Actin and Lck microcluster staining after 1 h culture on grid patterns; E. Statistical analysis of Lck microcluster size versus total cell size, and the percentage trend correlates with IL-2 secretion shown in A (*, p < 0.01; **, p < 0.005; ***, p < 0.00005).