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. Author manuscript; available in PMC: 2017 Apr 24.
Published in final edited form as: Nano Lett. 2016 Mar 23;16(4):2198–2204. doi: 10.1021/acs.nanolett.5b04364

Figure 5.

Figure 5

IMP compatibility for study of topography–drug combinations on cell expansion. A. Three inhibitors (latrunculin B, jasplakinolide, and blebbistatin) were tested for a drug/geometry combination effects on cell behavior. There is a drug/geometry interaction with 200 nm grids and blebbistatin; B. IL-2 secreted in supernatant after 2–3 days of culture on grid geometries with and without Blebbistatin. Two-way repeated measure ANOVA analysis shows significant enhancement in IL-2 secretion with Blebb and 200 nm trench geometry combination. (*, p < 0.02; **, p < 0.3; ***, p < 0.0002).