Table III.
Factors | No. of patients (n=195) | miR-21 high (n=88) | Positive rate, % | P-value |
---|---|---|---|---|
Gender | 0.65 | |||
Male | 112 | 49 | 43.8 | |
Female | 83 | 39 | 47.0 | |
Smoking status | 0.11 | |||
Non-smokers | 68 | 36 | 52.9 | |
Smokers | 127 | 52 | 40.9 | |
Tumor size, cm | 0.02 | |||
<3 | 136 | 54 | 39.7 | |
≥3 | 59 | 34 | 57.6 | |
Lymph node metastasis | 0.10 | |||
n (−) | 148 | 59 | 39.9 | |
n (+) | 47 | 29 | 61.7 | |
Lymphatic invasion | 0.29 | |||
Ly (−) | 153 | 66 | 43.1 | |
Ly (+) | 42 | 22 | 52.4 | |
Venous invasion | 0.56 | |||
V (−) | 122 | 57 | 46.7 | |
V (+) | 73 | 31 | 42.5 | |
Histological type | 0.87 | |||
Adenocarcinoma | 134 | 60 | 44.8 | |
Squamous cell carcinoma | 53 | 25 | 47.2 | |
Others | 8 | 3 | 37.5 | |
Tumor differentiation | 0.43 | |||
Well | 91 | 37 | 40.7 | |
Moderate | 74 | 35 | 47.3 | |
Poor | 30 | 16 | 53.3 | |
TNM stage | 0.03 | |||
I, II | 163 | 68 | 41.7 | |
III | 32 | 20 | 62.5 |
miR/miRNA, microRNA; TNM, tumor-node-metastasis.