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. 2017 Feb 28;13(4):2599–2606. doi: 10.3892/ol.2017.5788

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Copyright: © Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Oct4 expression enhances CSC property and invasion ability of HCC cell. (A) Oct4 enhances the abilities of sphere formation. (B) Oct4 enhances the abilities of soft agar colonization. (C) Oct4 enhances the abilities of Matrigel invasion. Graphs show the mean ± standard error of the mean from at least 3 experiments compared with mock cells. *P<0.05 was considered to indicate a statistically significant difference. Oct4, octamer 4; CSC, cancer stem cell; HCC, hepatocellular carcinoma; GFP, green fluorescent protein.