Effect of GGN administration on the concentration of (A) serum testosterone and (B) DHT production in prostate tissues of BPH-induced rat models. Values are expressed as the mean ± standard error of six rats per group. Experiments were performed once per sample. ###P<0.001 vs. Con group; ***P<0.001 vs. BPH group. GGN, Ga-Gam-Nai-Go-Hyan; DHT, dihydrotestosterone; BPH, benign prostatic hyperplasia; fina, finasteride-administered group; Con, sham-operated group.