Table VII.
Relation of single nucleotide polymorphisms (SNPs) to true or dissecting aortic aneurysm as determined by multivariable logistic regression analysis.
| SNP | Dominant
|
Recessive
|
Additive 1
|
Additive 2
|
||||
|---|---|---|---|---|---|---|---|---|
| P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | |
| True aortic aneurysm rs113710653 C/T (E231K) |
0.0002 | 5.32 (2.33–11.14) | 0.9263 | 0.0002 | 5.34 (2.34–11.18) | 0.9299 | ||
| Dissecting aortic aneurysm rs143881017 C/T (R140H) |
0.0006 | 5.77 (2.25–12.95) | 0.9615 | 0.0006 | 5.48 (2.26–12.97) | 0.9621 | ||
Multivariable logistic regression analysis was performed with adjustment for age, gender and the prevalence of hypertension. Based on Bonferroni's correction, P-values of <2.78×10−4 (0.05/180) or <6.58×10−4 (0.05/76) were considered statistically significant for true or dissecting aortic aneurysm, respectively, and are shown in bold. OR, odds ratio; CI, confidence interval.