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Results of quantitative polymerase chain reaction: Wild-type IDH mRNA was clearly detected in the specimens of the first and last (sixth) surgeries, and in the autopsy specimens (left column). The mutated IDH1 mRNA was consistently detected from the first surgical specimen onwards. The amplification was marginal but detectable in the last surgical specimen. However, in the autopsy specimen, mutated IDH mRNA could not be detected (right column, bottom).
