Table III.

Association between MAGE-A3/C2 mRNA expression and the clinicopathological characteristics of patients with non-small cell lung cancer in cohort 1.

	Cancer germline gene-expressing samples (%)
Clinicopathological characteristic	MAGE-A3	P-value	MAGE-C2	P-value	MAGE-A3/C2 coexpression	P-value
Age at diagnosis (years)
<65	74	0.733	57	0.072	50	0.002a
≥65	71		44		33
Gender
Male	76	0.238	50	0.109	43	0.228
Female	68		60		50
Histological grade
G1	69	0.694	50	0.872	39	0.310
G2	72		52		42
G3	77		55		52
Histological type
Squamous cell carcinoma	76	0.624	47	0.112	40	0.192
Adenocarcinoma	72		57		47
Lymph node metastasis
Present	84	0.012a	53	0.554	53	0.061
Absent	68		53		440
Tumor stage
I	66	0.006a	52	0.853	39	0.014a
II	79		54		54
III–IV	90		56		56
HLA-A2 expression
Positive	77	0.270	56	0.272	47	0.503
Negative	70		51		42

^aP<0.05. MAGE, melanoma-associated antigen; HLA, human leukocyte antigen.