Table I.
MUC1-VNTR1 | Sequence |
---|---|
Strong target gene | GCTAGCGCCACCATGCCGGGCTCCACCGCCCCCCCAGCCCACGGTGTCACCTCGGCCCCGGACACCAGGCCGGCCTGAGGTACC |
Weak target gene | GCTAGCGCCACCATGCACGGTGTCACCCGGCCCCGGACACCAGGCCGGCCCCGGGCTCCACCGCCCCCCCAGCCTGAGGTACC |
The strong target gene shows strong immunogenicity, as the PDTRP sequence has been added to the C-terminal end of MUC1-VNTR. The weak target gene shows weak immunogenicity, as the PDTRP sequence has been added to the N-terminal end of MUC1-VNTR. GCCACC is a Kozak sequence and the italic part refers to MUC1-VNTR1. MUC1, mucin 1; VNTR, variable number of tandem repeats.